Nasal nitric oxide and nasal allergy

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[Nasal nitric oxide].

Nitric oxide (NO) was considered an air pollutant until a few years ago. In the 1980s, Louis J. Ignarro and his team found that NO regulated vasodilatation and played an important role in several physiological processes in the cardiovascular system, discoveries that earned them the Nobel Prize in 1998. NO is now known to participate in such processes as hemostasis, the regulation of blood flow,...

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Nasal nitric oxide in man.

The past decade has witnessed an explosion in the interest of biologists in the gas nitric oxide (NO). This highly reactive free radical, first considered only a noxious air pollutant, is produced in mammalian cells by specific enzymes and is believed to play a vital role in many biological events including regulation of blood flow, platelet function, immunity, and neurotransmission. 2 Direct m...

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Measurement of nasal nitric oxide.

Nasal nitric oxide (nNO) is produced in high quantity in the upper airways. It is thought to be involved in host defence functions and regulation of mucociliary function, and to serve as a biochemical airborne transmitter. The measurement of nNO is easy and non-invasive. It has evolved as a screening test to exclude primary ciliary dyskinesia (PCD) in patients with suggestive symptoms, because ...

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Exhaled and nasal nitric oxide measurements: recommendations

*Dept of Thoracic Medicine, National Heart and Lung Institute, Dovehouse Street, London, UK. **Dept of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden. Correspondence. P.J. Barnes, Dept of Thoracic Medicine, National Heart and Lung Institute, Dovehouse Street, London SW3 6LY, UK. Received: April 3 1997; accepted for publication April 25 1997 This document was prepared follo...

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Nasal budesonide efficacy for nasal nitric oxide and nasal obstruction in rhinitis.

To the Editor, Nasal nitric oxide (nNO) is a non-invasive tool that may be helpful in evaluating the inflammatory status in the upper airways (1). Previous studies report that nNO is elevated in children with allergic rhinitis (AR) (2), especially in perennial sensitized subjects (3), and that it may be affected by topical administration of intranasal steroids (INSs) (4). Clinical studies repor...

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ژورنال

عنوان ژورنال: Allergy

سال: 2006

ISSN: 0105-4538,1398-9995

DOI: 10.1111/j.1398-9995.2006.01096.x